The Grandient solution!
"Son of Metrizamide"
Nycodenz Solution!(Nycoprep Universal 60%)
Sterile Ready-Made 60% (w/v) Solution in Water
Makes Density Gradient Solution: Simple
May be Sterilized by Autoclaving
1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION
Product name: Nycodenz
Application: Isolation of biological particles using centrifugation techniques
2. COMPOSITION, INFORMATION ON INGREDIENTS
Composition: Main ingredients: CAS No.: Content: Hazard classification:
Off-white powder 66108-95-0 None
3. HAZARDS IDENTIFICATION
Emergency overview: Powder. No hazard if spilled
Health Hazard: .Non-toxic
4. FIRST-AID MEASURES
General: Miscible with water.
Eyes: Flush eyes with water. If irritation occurs, seak medical advice.
Skin contact: Wash with water.
Ingestion: Wash mouth thoroughly with water and drink water if substance has been swallowed, drink large quantities of water.
Inhalation: Not applicable.
5. FIRE-FIGHTING MEASURES
Extinguishing media: Use extinguishing media appropriate for surrounding fire.
Flammable properties: Not flammable. This product does not present any fire or explosion hazard.
6. ACCIDENTAL RELEASE MEASURES
Personal precautions: Wear gloves, other protection is not necessary
Cleanup procedures: Clean up, contaminated area should be washed with soap and water.
7. HANDLING AND STORAGE
Handling precautions: Should be handled as an unknown chemical.
Storage precautions: Store in original container according to temperature stated on container and in package insert
8. EXPOSURE CONTROLS, PERSONAL PROTECTION
Ventilation: No particular ventilation requirements.
Protective gloves: Hand protection is recommended.
Eye protection: Eye protection not normally required.
Protective clothing: Protective clothing is not necessary.
9. PHYSICAL AND CHEMICAL PROPERTIES
Solubility: Readily miscible with water.
Spesific gravity: 2.1 g/ml
10. STABILITY AND REACTIVITY
Stability: Stable and not reactive
11. TOXICOLOGICAL INFORMATION
Acute Effects: None
Skin Effects: None
Eye Effects: None
12. ECOLOGICAL INFORMATION
Summary: This product is readily miscible with water and rated non- toxic. It has no potential for bioaccumulation.
13. DISPOSAL CONSIDERATION
General information: Disposal should be made in accordance with existing disposal practices employed for biological material
14. TRANSPORT INFORMATION
General information: Transportation of the product is not regulated by ADR. Fragile containers, handle with care. Protect from high temperatures.
15. REGULATORY INFORMATION
EU regulations: Not regulated under the European Community Directive 93/21/EEC.
16. OTHER INFORMATION
Revision Date: October 2000
Replaces: January 1992
This Safety Data Sheet complies to the European Community Directive 93/112/EC amended 91/155/EEC.
Dendritic Cell Therapy
|04-huIL1B-50 µg||human IL-1B, 50 µg||50µg||195 $|
|04-GMPhuIL4-50 µg||GMP human IL-4, 50 µg||50µg||399 $|
|04-RESIL4-100µg||Research human IL-4, 100 µg||100ug||245 $|
|04-RESIL4-50µg||Research human IL-4, 50 µg||50µg||195 $|
|04-huIL-6-50µg||human IL-6, 50 µg||50µg||195 $|
|04-huIL-10-50µg||human IL-10, 50 µg||50µg||195 $|
|04-huIL-11-1mg||human IL-11, 1mg||1mg||95 $|
|04-huIL-11-5mg||human IL-11, 5mg||5mg||195 $|
|04-huIL-15-50µg||human IL-15, 50 µg||50µg||195 $|
|04-RHUGM-CSF-300UG||mGMP GM-CSF, 300 µg||300µg||385 $|
|04-RHUGM-CSF-50UG||mGMP GM-CSF, 50 µg||50µg||90 $|
|04-HGH-4IU||HGH Lyophilisd powder||4IU||95 $|
|04-SOD-50µg||human SOD , 500 µg||500ug||195 $|
|04-RHUTNFA-50 µg||human TNF-a||50µg||399 $|
|04-GMPTAA- 10µg||GMP TAA’s Tumor Associated Antigens||10 µg||199 $|
|Different subpopulation of DCs can be obtained by separating and cultivating their precursors (for example monocytes) under different conditions. The most common subpopulation is obtained by using a combination of various cytokines, including interleukin 4 (IL-4) and granulocyte-monocyte colony-stimulating factor (GM-CSF)
In order to supply researchers and clinicians using DC with necessary tools of the trade, BruCells is developing preparations of these reagents suitable for the subsequent application of the DC to patients, i.e manufactured in accordance with Good Manufacturing Practice (GMP) and fulfilling state of the art specifications.
Cytokines are a class of proteins, which are secreted by living cells. They have several functions, such as promoting cellular growth, activate cells or destroy target cells such as cancer cells. A subgroup called Interleukins (IL) function as messengers between leukocytes. Cytokines have many potential applications. The demand is expected to grow in the future with the development of cellular therapies.
In the case of cellular immunotherapy of cancer, cytokines are mainly used for the maturation of DCs. For the moment, the market consists mainly of the many research and development groups which are working on therapeutic vaccines and which need to obtain reliable sources of clinical grade cytokines.
The production and marketing of clinical grade (GMP) human recombinant cytokines by BruCells present several advantages for the company:
Starting in August, 2004, clinical grade recombinant human Granulocyte-Monocyte Colony-Stimulating Factor can be supplied in vials containing 50 micrograms of lyophilized GM-CSF.
Research grade cytokines for experimental use in vitro can be provided subject to availability : IL-1b, IL-4, IL-6 and others. Please enquire.