Dendritic Cell Therapy
|04-huIL1B-50 µg||human IL-1B, 50 µg||50µg||195 $|
|04-GMPhuIL4-50 µg||GMP human IL-4, 50 µg||50µg||399 $|
|04-RESIL4-100µg||Research human IL-4, 100 µg||100ug||245 $|
|04-RESIL4-50µg||Research human IL-4, 50 µg||50µg||195 $|
|04-huIL-6-50µg||human IL-6, 50 µg||50µg||195 $|
|04-huIL-10-50µg||human IL-10, 50 µg||50µg||195 $|
|04-huIL-11-1mg||human IL-11, 1mg||1mg||95 $|
|04-huIL-11-5mg||human IL-11, 5mg||5mg||195 $|
|04-huIL-15-50µg||human IL-15, 50 µg||50µg||195 $|
|04-RHUGM-CSF-300UG||mGMP GM-CSF, 300 µg||300µg||385 $|
|04-RHUGM-CSF-50UG||mGMP GM-CSF, 50 µg||50µg||90 $|
|04-HGH-4IU||HGH Lyophilisd powder||4IU||95 $|
|04-SOD-50µg||human SOD , 500 µg||500ug||195 $|
|04-RHUTNFA-50 µg||human TNF-a||50µg||399 $|
|04-GMPTAA- 10µg||GMP TAA’s Tumor Associated Antigens||10 µg||199 $|
|Different subpopulation of DCs can be obtained by separating and cultivating their precursors (for example monocytes) under different conditions. The most common subpopulation is obtained by using a combination of various cytokines, including interleukin 4 (IL-4) and granulocyte-monocyte colony-stimulating factor (GM-CSF)
In order to supply researchers and clinicians using DC with necessary tools of the trade, BruCells is developing preparations of these reagents suitable for the subsequent application of the DC to patients, i.e manufactured in accordance with Good Manufacturing Practice (GMP) and fulfilling state of the art specifications.
Cytokines are a class of proteins, which are secreted by living cells. They have several functions, such as promoting cellular growth, activate cells or destroy target cells such as cancer cells. A subgroup called Interleukins (IL) function as messengers between leukocytes. Cytokines have many potential applications. The demand is expected to grow in the future with the development of cellular therapies.
In the case of cellular immunotherapy of cancer, cytokines are mainly used for the maturation of DCs. For the moment, the market consists mainly of the many research and development groups which are working on therapeutic vaccines and which need to obtain reliable sources of clinical grade cytokines.
The production and marketing of clinical grade (GMP) human recombinant cytokines by BruCells present several advantages for the company:
Starting in August, 2004, clinical grade recombinant human Granulocyte-Monocyte Colony-Stimulating Factor can be supplied in vials containing 50 micrograms of lyophilized GM-CSF.
Research grade cytokines for experimental use in vitro can be provided subject to availability : IL-1b, IL-4, IL-6 and others. Please enquire.