GP161 rabbit pAb

Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al. 2008 [PubMed 18250320]). [supplied by OMIM, Aug 2008],

23432

Q8N6U8

Cell projection, cilium membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein. Mainly localizes to primary cilium in a TULP3 and IFT-A complex-dependent manner. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes and is apparently not degraded (By similarity)..

Rabbit

Human, Rat, Mouse,

Synthesized peptide derived from human protein . at AA range: 180-260

Polyclonal

WB, ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

58kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.