Genprice

ACVR1 Antibody / ALK2

Supplier NSJ Bioreagents · Catalog number: F54224-0.08ML
Price

154 USD

Size
0.08ml

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.

  • Additional information:In 1X PBS, pH 7.4, with 0.09% sodium azide
  • Storage and shipping:Aliquot the ACVR1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

want a datasheet ?

want A Quote ?