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ARC Antibody

Supplier ProSci · Catalog number: 2081-002mg
Price

227 USD

Size
0.02 mg

ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

  • Additional information:Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
  • Storage and shipping:
    • ARC antibody can be stored at 4˚
    • C for three months and -20˚
    • C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Notes:Optimal dilutions for each application to be determined by the researcher.

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