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CTBP2 Antibody / C-terminal-binding protein 2

Supplier NSJ Bioreagents · Catalog number: V9175SAF-100UG
Price

384 USD

Size
100ug

The gene CTBP2 (C-terminal binding protein 2) encodes a member of the CtBP-family. The gene is mapped to human chromosome 21q21.3. It is found to be expressed ubiquitously, with higher expression in the heart, skeletal muscle, and pancreas. The gene CTBP2 (C-terminal binding protein 2) encodes a protein that functions as a transcriptional co-repressor of several tumor suppressor genes resulting in enhanced cancer cell migration and invasion. Its expression is found to be upregulated in hepatocellular carcinoma (HCC). It may be a potential prognostic marker for post liver resection HCC. It is involved in several types of tumor initiation, progression and response to therapy. It is found to interact with the C-terminal region of adenovirus type 2/5 E1A protein, a region that negatively regulates tumorigenicity and the extent of oncogenic transformation.

  • Additional information:
    • 1 mg/ml in 1X PBS
    • BSA free, sodium azide free
  • Storage and shipping:Aliquot the CTBP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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