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Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit

Supplier Abbkine · Catalog number: KTE61005-48T
Price

373 USD

Size
48T

This Human Glutaminyl-peptide cyclotransferase (QPCT) ELISA Kit employs a two-site sandwich ELISA to quantitate QPCT.

  • Additional information:QPCT encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. The deduced 361-amino acid protein has a calculated molecular mass of about 41 kD. It contains an N-terminal signal peptide region, several glycosylation and phosphorylation sites, and 2 cysteine residues conserved between the bovine and human enzymes. QPCT shares 86% overall sequence identity with the bovine homolog.Glutaminyl cyclase expression was upregulated in the cortices of individuals with Alzheimer disease and correlated with the appearance of pE-modified amyloid beta.
  • Storage and shipping:Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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