This Human Small proline-rich protein 2B (SPRR2B) ELISA Kit employs a two-site sandwich ELISA to quantitate SPRR2B.

• Additional information:SPRR genes encode a novel class of polypeptides called small proline-rich proteins that are strongly induced during differentiation of human epidermal keratinocytes in vitro and in vivo. SPRR genes constitute a distinct class of cornified envelope precursor proteins. Gibbs et al. (1993) concluded that there are 7 genes for the SPRR2 subfamily of small proline-rich proteins, including SPRR2B.Using DNA microarray analysis, Zimmermann et al. (2005) identified Sprr2a and Sprr2b as allergen-induced genes in a mouse model of experimental asthma.By analysis of human-rodent hybrid cell lines and FISH, Gibbs et al. (1993) determined that all SPRR genes, including SPRR2B, are closely linked within a 300-kb DNA segment on chromosome 1q21-q22.
• Storage and shipping:Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
• Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.