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ELISA kit for Mouse Dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1)

Supplier Abbkine · Catalog number: KTE71337-96T
Price

711 USD

Size
96T

Quantitative sandwich ELISA for measuring Mouse Dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:Dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1) encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. A complete lack of the encoded protein in mice results in embryonic lethality due to the disorganization of Reichert's membrane. Chimeric mice deficient in the encoded protein overcome embryonic lethality but develop a progressive muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. 
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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