Quantitative sandwich ELISA for measuring Mouse Laminin subunit alpha-1 (LAMA1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

• Additional information:Laminin is a basement membrane protein composed of 3 nonidentical chains, A (400 kD), B1 (230 kD), and B2 (220 kD), which are arranged in a cross-shaped structure. Mattei et al. (1989) used in situ hybridization to localize the human laminin A locus to chromosome 18p11.31.By study of mouse-Chinese hamster somatic cell hybrids, Kaye et al. assigned the gene for laminin A to mouse chromosome 17 and confirmed the assignment of the gene for laminin B2 to mouse chromosome 1. Haaparanta et al. reported the nucleotide sequence of LAMA cDNA. They found an open reading frame encoding 3,075 amino acids. Nissinen et al. reported that the complete human laminin A chain contains a 17-amino acid signal peptide and a 3,058-residue A chain proper. The chain has a distinct domain structure with numerous internal cysteine-rich repeats.
• Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
• Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.