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ELISA kit for Pig Spermatid nuclear transition protein 1 (TNP1)

Supplier Abbkine · Catalog number: KTE80009-48T
Price

467 USD

Size
48T

Quantitative sandwich ELISA for measuring Pig Spermatid nuclear transition protein 1 (TNP1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

  • Additional information:Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines. Yu et al. (2000) generated mice lacking the major transition nuclear protein, TP1, by targeted deletion of the Tnp1 gene in mouse embryonic stem cells. Surprisingly, testis weights and sperm production were normal in the mutant mice, and only subtle abnormalities were detected in sperm morphology. Electron microscopy showed large rod-like structures in the chromatin of mutant step 13 spermatids, in contrast to the fine chromatin fibrils observed in wildtype. Steps 12-13 spermatid nuclei from the testis of Tnp1- mice contained, in place of TP1, elevated levels of TP2 (TNP2) and some PRM2 precursor.
  • Storage and shipping:All of the components are shipped on ice packs/blue ice. Upon receiving the kit keep it at +4 degrees Celsius for up to 1 year (refer to the label on the box for the exact expiration date).
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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