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Rat Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) ELISA Kit

Supplier Abbkine · Catalog number: KTE100038-96T
Price

681 USD

Size
96T

This Rat Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) ELISA Kit employs a two-site sandwich ELISA to quantitate TRAIL.

  • Additional information:The protein encoded by Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
  • Storage and shipping:Storage: The unopened kit should be stored at 2 - 8°C. After opening, please store refer to protocols.Shipping:Gel pack with blue ice.
  • Notes:This kit is intended for research use only. It should not be used for human or animal clinical diagnostics or treatment.

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