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Filaggrin Antibody

Supplier NSJ Bioreagents · Catalog number: V3611SAF-100UG
Price

384 USD

Size
100 ug

Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

  • Additional information:
    • 1 mg/ml in 1X PBS
    • BSA free, sodium azide free
  • Storage and shipping:Store the recombinant Filaggrin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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