Jagged1 rabbit pAb

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008],

JAG1; JAGL1; Protein jagged-1; Jagged1; hJ1; CD339

182

P78504

Membrane; Single-pass type I membrane protein.

Rabbit

Human, Mouse, Rat

The antiserum was produced against synthesized peptide derived from the Internal region of human JAG1. AA range:981-1030

Polyclonal

IF, WB, IHC, ELISA

1 year

1 mg/mL

IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

140kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.