Product

MBP Monoclonal Antibody

Supplier Biovision · Catalog number: A1033-100
Price

348.00EUR

Size
100 ug

Mouse Monoclonal antibody recognizing Human antigen.

  • Additional information:
    • Antigen alternative names: Myelin A1 protein, Myelin membrane encephalitogenic protein
    • Accession number: P04370
    • Purification: Affinity purified mouse IgG using protein G
    • Background information: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
  • Storage and shipping:
    • Shipping: gel pack
    • Storage: -20 °C
    • Shelf life: 12 months
    • Handling: The antibody solution should be gently mixed before use.
  • Notes:For research use only.