Tissue Plasminogen Activator converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration. [UniProt]

• Additional information:Antibody in PBS with 0.02% sodium azide and 50% glycerol
• Storage and shipping:Store the tPA antibody at -20oC.