Biotin is a component of the B-complex vitamins that has been widely used in over-thecounter supplements. The effects of biotin on thyroid function tests (TFTs) have been recently reported by multiple authors. We report here a case of a patient who presented with TFTs consistent with hyperthyroidism and a positive radioactive iodine uptake (RAIU) scan while taking biotin supplements. The TFTs normalized almost a month later and continued to be normal even after resumption of biotin supplements. Interpreting TFTs while patients are taking biotin could pose a diagnostic challenge, so we suggest more frequent monitoring for those patients before starting them on long-term anti-thyroid medications.
HCV disease is among life threatening general medical issues around the world, with more than 170–200 million HCV infected individuals worldwide  including around 17 million patients from Pakistan . Liver cirrhosis and hepatocellular carcinoma is being caused by HCV. 27% of liver cirrhosis and 25% of hepatocellular carcinoma cases are caused mere due to Hepatitis C . Every year Hepatitis C cause around 350,000 individuals to loss their lives . HCV is a RNA virus with a single sense positive strand and belongs to the Flaviviridae family . Hepatitis C encodes for a polyprotein which is made of around 3010 amino acids , the genome of hepatitis C is 9.6 kb . The auxiliary proteins (C, E1, E2, and p7) and nonstructural proteins (NS2, NS3, NS4A, NS4B, NS5A, and NS5B) are created by this polyprotein when it is post translationally handled by viral and cell proteins .
To specialize stem cells more than 350 clinical trials are underway to test tissue self-repair. The few hundred researchers gathered at the beginning of October in Marseille, at the 5th congress of the International Society of Plastic and Regenerative Surgeons, see little limit to its future applications. For its organizer Guy Magalon, a pioneer of plastic and reconstructive surgery, cell therapy “touches humanity in its flesh by promising eternal life”. Or, if not immortality, at least an increased longevity in good form. In the service of Professor Philippe Menasché at the Georges Pompidou European Hospital, of the first patient suffering from a heart attack and treated successfully. using cardiac cells derived from human embryonic stem cells. Six patients have since benefited from this technique, which uses a regenerating patch made from a fibrin “net” – a protein in the blood plasma – that can be placed as a dressing on the area injured by an infarct.
GFP Green fluorescent protein was isolated in jellyfish, Aequorea Victoria. The protein consists of 238 amino acid residues that fluoresce green when exposed to UV light. This method makes it possible to study proteins in their natural environment: the living cell. The gene for GFP was successfully inserted into E. coli bacteria in 1994 and the 2008 Nobel Prize in Chemistry was awarded to Osamu Shimomura, Martin Chalfie and Roger Y. Tsien for Discovery and Development. GFPs.
Nucleic acid amplification is a widely used method for the diagnosis and management of infectious diseases. The interpretation of Polymerase Chain Reaction (PCR) results varies depending on the pathogens detected, the site of infection and the clinical presentation. For some infections, PCR tests are now considered a reference method while for others they are only a diagnostic aid. With the development of antiviral treatments, quantitative PCRs have become indispensable for the evaluation of therapeutic efficacy. Contact with the laboratory performing the analysis is important in order to interpret the PCR results correctly
Gentaur stands for Genetics,genes, heredity, and variation in living organisms and laboratory equipment for exclusive use by public or private research organizations. The application of science and technology to living organisms, as well as its components, products and models, to modify living or non-living materials for the production of knowledge, goods and services. Thus, you can find all biological products covering all aspects of basic and applied research in the fields of molecular biology, cell biology, microbiology, immunology, virology, biochemistry, etc.
Monoclonal antibodies are identical because they are produced by a clone of plasmocytes. Monoclonal antibodies are widely used in biology and medicine, both as diagnostic tools and for therapeutic purposes.
Monoclonal antibodies or also known as (MAB) or (moAb) are identical antibodies that are produced in a laboratory from a single clone of B cells. The B cells that are used are also identical, and that is why these antibodies have specifity, and they recognize only one specific antigen, and bind to the same epitope.
Polyclonal antibodies (PA or pAbs ) are produced by different type of B cells lineages. Therefore, this type of antibodies has different structure even if they bind to the same antigen, just slightly different region (epitope).
A US team of scientists managed to publish the genome of reptiles for the first time with the Crispr gene editing tool, creating mini-lizards albino. The manipulation could improve our understanding of sight problems in humans, hope the researchers.