TmpA partial (23-41aa and 288-325aa) Treponema Pallidum Membrane Protein A Treponema pallidum, recombinant, E. coli

The E. coli derived 68kDa recombinant protein contains the Trp. Pallidum TmpA immunodominant regions, 23-41 amino acids and 288-325 amino acids. Treponema pallidum is a gram-negative spirochaete bacterium and is considered to be metabolically crippled. There are at least four known subspecies: T. pallidum pallidum, T. pallidum pertenue, T. pallidum carateum and T. pallidum endemicum. The helical structure of T. pallidum pallidum allows it to move in a corkscrew motion through viscous mediums such as mucus. Treponema pallidum sub sp. pallidum has one of the smallest bacterial genomes at 1.14 million base pairs (Mb) and has limited metabolic capabilities, reflecting its adaptation through genome reduction to the rich environment of mammalian tissue.

Immunoreactive with sera of T. pallidum infected individuals.

12352202

Proteins

N/A

35079090

34160400

Peptide and Protein

Treponema Pallidum protein binds to murine anti-TmpA protein monoclonal antibodies and Treponema pallidum converted human serum polyclonal antibodies in ELISA and Western Elisa. For Dot Blots and Lateral Flow immunochromatographic diagnostic tests.

N/A

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> 90 % (SDS-PAGE)

Liquid (Supplied in 10 mM Tris-HCl pH 8.0, 20 mM DDT, 1 mM EDTA and 8 M urea)

N/A

N/A

N/A

false

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N/A

N/A

Shipped on gel packs.

Store at -20 °C. Avoid freeze/thaw cycles.

12 months