IvTech the Advanced Cell Culture Chambers

The IvTech cell culture chambers allow a significant upgrade of the classic tests to better represent the in-vivo environment and physiologically-like conditions.

LiveBox1 is a transparent chamber designed for inter-connected dynamic cell cultures. LB1 is featured with a flow inlet and outlet for the perfusion of cell culture media. The clamp system provided with the LB1 assures the watertight closure of the system in both static and dynamic conditions (up to 1 mL/min).
– Wet volume 1.5 mL
– Suggested flow rate 0.1 to 0.4 mL/min

LiveBox1 LB1 Features

– The ivtech cell culture LB1 is designed to reproduce the typical volume of a 24 well plate
– The removable transparent glass bottom allows for:
– Live imaging during static/dynamic culture, i.e. in situ imaging of the three-dimensional culture environment using microscopy techniques.
– Post culture imaging including staining procedures or any other sample processing. After disassembling the LB1, the glass slide supporting the cell monolayer or 3D construct can be easily removed from its bottom part and used for further investigations and analysis.
– Modularity: LB1 can be inter-connected with other cell culture chambers in order to mimic cross talk between tissues (multi organ simulation).
LB1 can be ordered alone or as a kit (LB1 kit).

ivtech-livebox1-2-specifications

LiveBox2 is transparent chamber, developed to model physiological barriers (e.g. lung and intestinal epithelium) in-vitro. LB2 is designed for inter-connected dynamic cell cultures and is equipped with two flow inlets and outlets, and a holder to house a porous membrane. The clamp system provided with the LB2 assures the watertight closure of the system in both static and dynamic conditions (up to 0.5 mL/min in apical or basal compartments).
– Wet volume 1.5 mL
– Interface conditions ALI, LLI
– Suggested membrane diameter 25 mm
– Suggested membrane thickness Up to 0.1 mm

LiveBox2 Specifications

The system is designed to reproduce the typical surface of a 12 transwell.
The removable transparent glass bottom allows for:
Live imaging during static/dynamic culture, i.e. in situ imaging of the three-dimensional culture environment using optical microscopy.
The removable holder system allows for:
– Housing of a porous membrane
– Easy and safe handling of the membrane where cells are seeded
– Post culture imaging including staining procedures or any other sample processing. After disassembling the LB2, the holder system supporting the cultivated cell monolayer or 3D construct can be easily removed from the bottom part and used for further investigations and analysis.
– Modularity: LB2 can be connected with other cell culture systems in order to mimic cross talk between tissues (multi organ simulation).

LB2 can be ordered alone or as a kit (LB2 kit).

ivtech-livebox1-2-specifications
ivtech-liveflow

LiveFlow LF

LiveFlow is a compact and low weight peristaltic pump, compatible with the incubator environment. Two removable heads drive up to two independent circuits/head. LiveFlow is equipped with a drawer able to house up to four bioreactors. Therefore you can perform up to four independent experiments in parallel. The intuitive and user-friendly interface permits a quick and easy set-up of the system, with two independent heads able to apply a flow rate between 100-450 µL/min.
– Dimensions 21.5×16×14.5 w×l×h, cm
– Power supply (by provided cable) 12 V; 7.2 W
– Flow rate range 100-450 µL/min
– Weight 1.2 Kg

LiveFlow Features

– LiveFlow is compatible with the incubator environment
– Its small weight allows an easy transfer of the LiveFlow pump from the laminar hood to the incubator/microscope
– LiveFlow is equipped with two pumping heads, each one driving two independent circuits
– Each pumping head is removable, sterilisable and reusable
– LiveFlow is equipped with a drawer that houses up to four LiveBoxes. The design allows chambers monitoring using an inverted microscope
– The interface is intuitive and user friendly: a couple of buttons allows an easy setting of flow rates, a display shows the flow rate selected for each head, flow direction can be reverted through a dedicated button
LF can be ordered alone or as a starter kit (SK01 or SK02).

ivtech-liveflow-features
Djoumana Ounas

Djoumana Ounas

Pharmacist Assistant Professor in Analytical Chemisty. Consultance Expertise and Reglatory Biotech Support.

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