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BMP-15 rabbit pAb

CAT:ES4376-01Size:50 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016],

Synonyms:

BMP15; GDF9B; Bone morphogenetic protein 15; BMP-15; Growth/differentiation factor 9B; GDF-9B

Gene ID:

9210

UniProt:

O95972

Cellular Locus:

Secreted.

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human BMP15. AA range:291-340

Clonality:

Polyclonal

Validated Applications:

WB,IHC,IF,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Molecular Weight:

45kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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Product Datasheet:

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