Anti-Mammaglobin (SCGB2A2) (Breast Cancer Marker) (MGB1/2000), CF740 conjugate

Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Mammaglobin-1 (MGB1); Mammaglobin-A; Secretoglobin family 2A member 2 (SCGB2A2); SG2A2; UGB2

41116161

Primary and secondary antibodies for multiple methodology
immunostaining detection application

SCGB2A2

4250

46452

Q13296

Secreted (extracellular)

Mouse

Human

Recombinant full-length human Mammaglobin (SCGB2A2) protein

Mammaglobin

Monoclonal

IgG1 κ

MGB1/2000

CF740

Tumor

Animal

IHC, FFPE (verified) | WB (verified)

IHC, FFPE, WB

Cancer

SK-BR-3 cells or Breast Carcinoma

0.1 mg/mL

PBS, 0.1% rBSA, 0.05% azide

18 kDa

Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistology (formalin): 0.1-0.2 ug/mL for 30 minutes at RT|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 minutes followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user

Room temperature

4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.

2 years

Primary

https://biotium.com/product/mammaglobin-monoclonal-mouse-antibody-mgb1-2000