CELA3B Antibody / Elastase 3B

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

P08861

Mouse

A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.

Monoclonal

IgG1 κ

ELISA, WB, IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Elastase 3B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Elastase 3B antibody is available for research use only.

Primary antibody

https://www.nsjbio.com/tds/elastase-3b-antibody-cela3b-1257-v3436