Dsg1 rabbit pAb

This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],

Desmoglein-1 (Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen)

1828

Q02413

Cell membrane ; Single-pass type I membrane protein. Cell junction, desmosome.

Rabbit

Human,Mouse,Rat

Synthetic peptide from human protein at AA range: 30-90

Polyclonal

WB,IHC,IF,ELISA

1 year

1 mg/mL

WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

160kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.