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E2F-5 rabbit pAb
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 inter
E2F5; Transcription factor E2F5; E2F-5
1875
Q15329
Nucleus.
Rabbit
Human, Mouse, Rat
The antiserum was produced against synthesized peptide derived from human E2F-5. AA range:93-142
Polyclonal
WB, ELISA
1 year
1 mg/mL
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
36kD
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
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