GDF-8 rabbit pAb

Myostatin (MSTN) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. [provided by RefSeq, Jul 2016],

MSTN; GDF8; Growth/differentiation factor 8; GDF-8; Myostatin

2660

O14793

Secreted.

Rabbit

Human,Mouse

The antiserum was produced against synthesized peptide derived from human GDF-8. AA range:38-87

Polyclonal

WB,IHC,IF,ELISA

1 year

1 mg/mL

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.