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HES2 rabbit pAb

CAT:ES10672-01Size:50 μLPrice:Ask for quotation

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description:

Domain: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG). Domain: The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins. function: Transcriptional repressor of genes that require a bHLH protein for their transcription. similarity: Contains 1 basic helix-loop-helix (bHLH) domain. similarity: Contains 1 Orange domain. subunit: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family. tissue specificity: Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.

Gene ID:

54626

UniProt:

Q9Y543

Cellular Locus:

Nucleus.

Host:

Rabbit

Species Reactivity:

Human,Rat,Mouse,

Immunogen:

Synthesized peptide derived from human protein . at AA range: 40-120

Clonality:

Polyclonal

Validated Applications:

WB,ELISA

Stability:

1 year

Concentration:

1 mg/mL

Dilution:

WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight:

19kD

Storage Conditions:

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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Product Datasheet:

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