N2DL1 rabbit pAb

The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],

80329

Q9BZM6

Cell membrane ; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi..

Rabbit

Human,Rat,Mouse,

Synthesized peptide derived from part region of human protein

Polyclonal

WB,ELISA

1 year

1 mg/mL

WB 1:500-2000 ELISA 1:5000-20000

26kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.