Nkx-2.8 rabbit pAb

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015],

26257

Q8IUT7

Nucleus,

Rabbit

Human,Rat,Mouse,

The antiserum was produced against synthesized peptide derived from human NKX28. AA range:20-69

Polyclonal

WB,ELISA

1 year

1 mg/mL

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

26kD

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.