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Org-24598
CAT:HY-10712Size:InquirePrice:Ask for quotation
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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This product ships without dry ice.
Clinical Information:
No Development Reported
CAS Number:
372198-97-5
UNSPSC Description:
Org-24598 is an inhibitor of glycine transporter 1 GlyT-1 . Org-24598 can inhibit the specific binding of [3H] CHIBIA-3007 to the rat brain membranes with a Ki value of 16.9 nM[1].
Target Antigen:
GlyT
Type:
Reference compound
Related Pathways:
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications:
Neuroscience-Neuromodulation
Field of Research:
Neurological Disease
Assay Protocol:
https://www.medchemexpress.com/org-24598.html
Solubility:
10 mM in DMSO
Smiles:
CN(CC(O)=O)CC[C@@H](OC1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2
Molecular Weight:
367.36
References & Citations:
[1]Zhang J, et al. Pharmacological characterization of [³H]CHIBA-3007 binding to glycine transporter 1 in the rat brain. PLoS One. 2011;6(6):e21322.
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Room temperature
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