Surfactant protein D Antibody / SFTPD

Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials.

P35247

Mouse

A recombinant partial protein (within amino acids 241-336) from the human protein was used as the immunogen for the Pulmonary Surfactant-Associated Protein D antibody.

Monoclonal

IgG2b λ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the Pulmonary Surfactant-Associated Protein D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Pulmonary Surfactant-Associated Protein D antibody is available for research use only.