IL18RAP Antibody / CD218b

The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]

O95256

Mouse

A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Interleukin-18 receptor accessory protein antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the Interleukin-18 receptor accessory protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Interleukin-18 receptor accessory protein antibody is available for research use only.