Bax Recombinant Antibody

Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Q07812

Rabbit

Recombinant full-length human BAX protein was used as the immunogen for the recombinant Bax antibody.

Monoclonal

IgG κ

Recombinant

WB

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the recombinant Bax antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant Bax antibody is available for research use only.