CYP2E1 Recombinant Antibody

The CYP2E1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [RefSeq]

P05181

Rabbit

A synthetic peptide specific to human CYP2E1 was used as the immunogen for the Cytochrome P450 2E1 antibody.

Monoclonal

IgG

Recombinant

WB

Purified

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Store the Cytochrome P450 2E1 antibody at -20oC.

This Cytochrome P450 2E1 antibody is available for research use only.