Vinculin Recombinant Antibody

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including Talin and -Actinin has been shown to link Actin to integrins in the plasma membrane through interactions with the vinculin and Talin complex or by a direct interaction with integrin.

P18206

Rabbit

A portion of amino acids 174-322 was used as the immunogen for the recombinant Vinculin antibody.

Monoclonal

IgG

Recombinant

WB, IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Aliquot the recombinant Vinculin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant Vinculin antibody is available for research use only.

Primary antibody

http://www.nsjbio.com/tds/recombinant-vinculin-antibody-vcl-7091r-v9615