Alpha-2-macroglobulin Recombinant Antibody / A2M

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [RefSeq]

P01023

Rabbit

A synthetic peptide specific to human A2M / Alpha 2 Macroglobulin was used as the immunogen for the Alpha-2-macroglobulin antibody.

Monoclonal

IgG

Recombinant

WB

Purified

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA

Store the Alpha-2-macroglobulin antibody at -20oC.

This Alpha-2-macroglobulin antibody is available for research use only.