Anaplastic Lymphoma Kinase Antibody (ALK)

Anaplastic lymphoma kinase, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2;5)(p23;q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.

Q9UM73

Rabbit

A portion of amino acids 636-666 from the human protein was used as the immunogen for this ALK antibody.

Polyclonal

Ig

WB, IHC, ELISA

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the ALK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This ALK antibody is available for research use only.