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CD43 Recombinant Antibody
It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
P16150
Rabbit
Recombinant full-length human protein was used as the immunogen for the recombinant CD43 antibody.
Monoclonal
IgG κ
Recombinant
IHC-P
Purified
1 mg/ml in 1X PBS; BSA free, sodium azide free
Aliquot the recombinant CD43 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
This recombinant CD43 antibody is available for research use only.
Primary antibody
http://www.nsjbio.com/tds/recombinant-cd43-antibody-spn-6562r-v9537
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