Cdc20 Recombinant Antibody

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. [UniProt]

Q12834

Rabbit

Recombinant human Cdc20 protein was used as the immunogen for the recombinant Cdc20 antibody.

Monoclonal

IgG κ

Recombinant

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Aliquot the recombinant Cdc20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This recombinant Cdc20 antibody is available for research use only.

Primary antibody

http://www.nsjbio.com/tds/recombinant-cdc20-antibody-cdc20-7026r-v9446