Nestin Antibody

Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations.

P48681

Rabbit

A portion of amino acids 1560-1590 from the human protein was used as the immunogen for this Nestin antibody.

Polyclonal

Ig

IHC, IF, ELISA

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Nestin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Nestin antibody is available for research use only.