NSE Antibody / Neuron Specific Enolase

This monoclonal antibody recognizes a protein of about 50kDa, which is identified as gamma-enolase. Three isoenzymes of enolases are identified, alpha, beta and gamma. Alpha-isoform is expressed in most tissues, whereas beta-form is expressed predominantly in muscle tissue whereas gamma-enolase is found only in nervous tissue. These isoforms exist as both homodimers and heterodimers, and they play a role in converting phosphoglyceric acid to phosphenolpyruvic acid in the glycolytic pathway. NSE-gamma is a useful marker to identify peripheral nerves and tumors of neuro-endocrine origins, such as pheochromocytomas.It it be usually employed in combination with other markers such as Synaptophysin,Chromogranin A, and Neurofilament.

P09104

Mouse

Amino acids 416-433 of human Neuron-specific Enolase were used as the immunogen for this NSE antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Store the NSE gamma antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This NSE gamma antibody is available for research use only.