CD105 Antibody / Endoglin

Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. [UniProt]

P17813

Mouse

Amino acids 74-251 were used as the immunogen for the CD105 antibody.

Monoclonal

IgG2b κ

IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the CD105 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This CD105 antibody is available for research use only.