Adrenomedullin antibody / ADM

ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.

P35318

Rabbit

A portion of amino acids 69-96 from the human protein was used as the immunogen for the Adrenomedullin antibody.

Polyclonal

IgG

WB, FACS

Purified

In 1X PBS, pH 7.4, with 0.09% sodium azide

Aliquot the Adrenomedullin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This Adrenomedullin antibody is available for research use only.