Androgen Receptor Antibody

The Androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. [RefSeq]

P10275

Mouse

Recombinant full-length human AR protein was used as the immunogen for the Androgen Receptor antibody.

Monoclonal

IgG1 κ

IHC-P

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Store the Androgen Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Androgen Receptor antibody is available for research use only.