CD68 Antibody

This gene encodes a 40~110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

P34810

Rabbit

A portion of amino acids 209-237 from the human protein was used as the immunogen for this CD68 antibody.

Polyclonal

Ig

WB, ELISA

Antigen affinity purified

In 1X PBS pH 7.4 with 0.09% sodium azide

Aliquot the CD68 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

This CD68 antibody is available for research use only.