Cystatin A Antibody / CSTA

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

P01040

Mouse

A recombinant human partial protein (amino acids 1-98) was used as the immunogen for the Cystatin A antibody.

Monoclonal

IgG2c κ

IHC-P

Purified

0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Store the Cystatin A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Cystatin A antibody is available for research use only.