Estrogen Receptor beta 2 Antibody

This MAb recognizes the estrogen receptor beta 2 isoform, expressed in cell nuclei of a range of human tissues including ovary, placenta, testis and vas deferens. No cross-reactivity is seen with estrogen receptor beta 1 isoform. This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members.

Q92731

Mouse

Amino acids CGMKMETLLPEATMEQ from the C terminus of the human estrogen receptor beta 2 isomer were used as the immunogen for the Estrogen Receptor beta 2 antibody.

Monoclonal

IgG1 κ

FACS, IF, WB, IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Estrogen Receptor beta 2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Estrogen Receptor beta 2 antibody is available for research use only.