+1 (408)780-0908
Granzyme B Antibody
CAT:V7638SAF-100UGSize:100 µgPrice:Ask for quotation
Availability:
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Shipping:
This product ships with dry ice.
Description:
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis. [UniProt]
UniProt:
P10144
Host:
Mouse
Immunogen:
Amino acids 73-187 were used as the immunogen for the Granzyme B antibody.
Clonality:
Monoclonal
Isotype:
IgG2b κ
Applications:
WB, IHC-P
Format:
Purified
Buffer:
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution:
Store the Granzyme B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations:
This Granzyme B antibody is available for research use only.
