Histone H1 Recombinant Antibody

Five major families of histones exist: H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1/H5 are known as the linker histones. The core histones all exist as dimers, which are similar in that they all possess the histone fold domain; three alpha helices linked by two loops. It is this helical structure that allows for interaction between distinct dimers, particularly in a head-tail fashion (also called the handshake motif). The linker histone H1 binds the nucleosome at the entry and exit sites of the DNA, thus locking the DNA into place and allowing the formation of higher order structure. [Wiki]

P07305

Rabbit

Recombinant full-length human protein was used as the immunogen for the recombinant Histone H1 antibody.

Monoclonal

IgG κ

Recombinant

IHC-P, IF, FACS

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the recombinant Histone H1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This recombinant Histone H1 antibody is available for research use only.