IL1RA Antibody / Interleukin-1 Receptor Antagonist / IL1RN

The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

P25086

Mouse

An E. coli-derived rat protein (amino acids H27-Q178) was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody.

Monoclonal

IgG2b

ELISA (Capture)

Antigen affinity purified

0.5mg/ml if reconstituted with 0.2ml sterile DI water

After reconstitution, the Interleukin-1 Receptor Antagonist antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

This Interleukin-1 Receptor Antagonist antibody is available for research use only.