Kappa Light Chain Antibody

This antibody is specific to the kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general, the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Mouse

Human B-Lymphoma Cells were used as the immunogen for this Kappa Light Chain antibody.

Monoclonal

IgG1 κ

WB, IHC-P

Purified

1 mg/ml in 1X PBS; BSA free, sodium azide free

Store the Kappa Light Chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

This Kappa Light Chain antibody is available for research use only.